Mean Velocity of Fiber Shortening

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Mean Velocity of Fiber Shortening

Previously it was shown that left ventricular (LV) myocardial contractility can be assessed from the instantaneous relation between velocity of fiber shortening and maximum LV wall tension (VcF at max T). Such analysis is complex, requiring frame-by-frame correlation of LV dimensions with pressure, and a simpler approach was sought. In 50 patients the mean velocity of circumferential fiber shor...

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Myocardial blood flow in congestive and hypertrophic cardiomyopathy: relationship to peak wall stress and mean velocity of circumferential fiber shortening.

Myocardial blood flow/unit mass (MBF) and the determinants of myocardial oxygen consumption were measured in seven control subjects (group I) and 15 patients (pts) with cardiomyopathy (CM), group II (group IIa-congestive CM: 10 pts; group IIb-hypertrophic CM: 5 pts). In group I left ventricular (LV) MBF was 64 +/- 8 (SD) ml/100g-min; it was significantly lower in IIa (45 +/- 15 ml/100g-min, P l...

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Skeletal muscle fiber atrophy: altered thin filament density changes slow fiber force and shortening velocity.

Single skinned fibers from soleus and adductor longus (AL) muscles of weight-bearing control rats and rats after 14-day hindlimb suspension unloading (HSU) were studied physiologically and ultrastructurally to investigate how slow fibers increase shortening velocity (V0) without fast myosin. We hypothesized that unloading and shortening of soleus during HSU reduces densities of thin filaments, ...

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A noninvasive technique for the determination of velocity of circumferential fiber shortening in man.

Velocity of circumferential fiber shortening (V0F) as determined by analysis of left ventricular cineangiocardiograms has been proposed as a measure of left ventricular myocardial contractility. In this study, a noninvasive ultrasonic technique was used to measure the rate of shortening of the left ventricular internal minor axis throughout ejection in 61 patients. These measurements permitted ...

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Comparison of ultrasound and cineangiographic measurements of the mean rate of circumferential fiber shortening in man.

mean VCF by this noninvasive technic in patients studied by both methods. In 15 patients considered to have normal left ventricular function, the average mean VOF determined by ultrasound was 1.29 + 0.23 circumferences/sec, while in the 13 patients with reduced left ventricular performance this value was 0.75 + 0.16 circumferences/ sec (P < 0.001). Values of mean VCF by the two technics were si...

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ژورنال

عنوان ژورنال: Circulation

سال: 1971

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.44.3.323